By Cindy Schmidt, M.D., M.L.S.

published 06/01/2015

updated 07/26/2018

 

Complete episode 1, episode 2, and episode 3 before beginning this episode.

 

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Learning Issues # _____

During this afternoon's PBL session and during your work on this tutorial miniseries, you've collected a list of diagnoses that often present with epigastric pain (a differential diagnosis list).

However, it's possible that you haven't yet considered the implications, if any, of  John's past medical and social histories (PMH and SH).  Specifically:

 

Learning issue #8. Does surgery for pyloric stenosis during infancy have any longterm implications in adulthood?

Learning issue #9. Do medical students experience increased rates of gastrointestinal problems?

 

Both of these learning issues include multiple search concepts.  Not all search engines can handle more than one concept.

Resources that can handle multi-concept searches

Resources that will work for this type of robust search include --

1) AccessMedicine's Advanced Search (lower search box on "Advanced Search" page)

2) UpToDate

3) PubMed and other literature databases that index the journal literature.

4) Google or Google Scholar

 You used the AccessMedicine ebook collection during episode 1, and  UpToDate for learning issues 8 and 9.   So, for these learning issues, start with a PubMed search for relevant journal articles. 

These two learning issues are the types of very specific issues that are best addressed by the journal literature in any case. 

 

PBL Journal Article Requiremet

Each student is expected to bring at least one journal article to one of the three sessions for each of your PBL cases.

It's worth taking some time to practice PubMed search techniques and methods for obtaining full-text articles now.

PubMed

PubMed is the U.S. government's means for providing access to:

  • MEDLINE, the premier database indexing the biomedical, journal literature.
  • PREMEDLINE records (records waiting to be indexed in MEDLINE),
  • records for articles in PubMed Central (a full-text depository) and
  • a comparatively small number of records for online reports and book chapters.

A reminder: During episode 3, you used MedlinePlus. Remember, MEDLINE contains records for professional-level, journal articles. It is part of PubMed. MedlinePlus contains links to authoritative, lay-level information on the internet. It is not part of PubMed.

Accessing PubMed

To reach the version of PubMed that contains UNMC's full-text buttons:

  • Go to the Library's homepage.

In the future, you can reach the library's homepage by going to any unmc.edu page and clicking the "Library" link at the bottom of the "Quick Links" in the lower right-hand corner of the page.)

  • Click on the "Literature Databases" button.

screenshot of McGoogan Library homepage with arrow pointing to Literature Databases link

  • Click on the "MEDLINE via PubMed" link.
  • If asked, login with your UNMC Net ID

PubMed Search: Step 1. Concepts

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The first step in conducting a PubMed search is listing the search concepts.

Open a Word document. In the document type terms for the important concepts in the two searches:

Search 1. Does surgery for pyloric stenosis during infancy have any longterm implications in adulthood?

Search 2. Do medical students experience increased rates of gastrointestinal problems?

 

PubMed Search: Step 1. Concepts

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Did you say that the important concepts were:

____________

search 1:

Surgery

pyloric stenosis

infancy

longterm

adult

_____________

search 2:

medical students

gastrointestinal, dyspepsia

______________

 

If so, great job!

It's possible that you included the phrase --

gastrointestinal problems

-- rather than the word -- gastrointestinal.  This is totally reasonable.  You'll understand the reason for avoiding the phrase -- gastrointestinal problems -- after completing the next step in search construction.

PubMed Search: Step 2. Synonyms, Alternate Terms

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Today, you'll conduct a keyword search. A keyword search is a search in which you try to guess which words an author would have used in an article's title or abstract to indicate a discussion of your search concepts. Later this year, you'll be asked to conduct the other type of PubMed search ( a medical subject heading search).

The next step in a keyword search is listing important synonyms or alternate terms for your search concepts.

List important synonyms and alternate terms next to the concept terms in your Word document.

PubMed Search: Step 2. Synonyms, Alternate Terms

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Did you list any of the alternate terms shown below? 

____________

Search 1

Surgery, surgeries, surgical, operative, operation, operations, post-operative, postoperative

pyloric stenosis

infancy, infantile, infant, infants, newborn, newborns, neonate, neonates, neonatal, baby, babies

longterm, long-term,  long term

adult, adulthood, adults

_____________

Search 2

medical students, medical student

gastrointestinal, gastric, intestinal,  stomach, bowel, bowels,  dyspepsia, pyloric, pylorus, duodenum, duodenal, ulcer, ulcers, gastritis, reflux, gerd, gastroesophageal, esophageal, Crohn's, ibs

______________

 

If so, good job!

Add any terms you missed to your word document.

PubMed Search: Step 2. Synonyms, Alternate Terms

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There are actually many more relevant terms, especially for the "gastrointestinal" concept. 

Imagine how much worse the "gastrointestinal" term list would be if you had to include all the synonyms for "gastrointestinal problems", in both singular and plural form.  Plural versions alone include:

gastrointestinal problems, gastrointestinal conditions, gastrointestinal diseases, gastric problems, intestinal problems, gut problems, bowel problems, etc., etc. 

It's easier to just deal with the synonyms for the word "gastrointestinal."  If the search with the word gastrointestinal and its synonyms retrieve too many irrelevant results, the search can be revised.

 

PubMed Search: Step 3. Truncation

1 of 2The next step is deciding whether you want to truncate any terms.
  • If a word you've listed  has multiple useful forms, shorten the word to the trunk shared by all the useful forms and add an asterisk (*). The asterisk acts as a wildcard.
  • Remove terms from your list that are made unecessesary by your truncated terms.

For example, the search term --

infan*

-- will retrieve PubMed records containing any of the following terms --

infant
infants
infancy
infantile
 

Warnings

Multi-word phrases should not be truncated in PubMed.

Avoid using one syllable word trunks. For example, it would be unwise to use --

bab*

-- as a substitute for baby and babies. Bab* will retrieve records containing

baby
babies

--but will also retrieve many irrelevant words, e.g. --

babble
babbling
babinski
babesiosis
baboons, etc.

 

PubMed Search: Step 3. Truncation

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Do your term lists look something like the following?

____________

Search 1

Surger*, surgical*, operat*, post-operative, postoperative

pyloric stenosis

infan*, newborn*, neonat*, baby, babies

longterm, long-term, long term

adult*

_____________

Search 2

medical students, medical student

gastrointestinal, gastric, intestinal, stomach, bowel*,  dyspepsia, pyloric, pylorus, duoden*, ulcer*, gastritis,reflux, gerd, gastroesophageal, esophageal, Crohn*, ibs

______________

PubMed Search: Step #4. Enclose Phrases in Quotation Marks

  • Next enclose the multi-word search terms in quotes -- e.g.

"medical students"

 

The quotes tells the PubMed search engine that you  only want to retrieve records in which the enclosed words are adjacent and in the order shown.

PubMed Search: Step #5 -- Join alternate terms with OR

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  • Now join the alternate terms for each concept with OR while simultaneously removing any punctation between terms, e.g.

 

Surger* OR surgical* OR operat* OR post-operative OR  postoperative

 

The OR's tell the search engine that you don't care which of the terms is present.

PubMed Search: Step #5 -- Join alternate terms with OR

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Does your work look something like the following?

____________

Search 1

Surger* OR surgical* OR operat* OR post-operative OR postoperative

"pyloric stenosis"

infan* OR newborn* OR neonat* OR baby OR babies

longterm OR long-term OR "long term"

adult*

_____________

Search 2

"medical students" OR "medical student"

gastrointestinal OR gastric OR intestinal OR stomach OR bowel* OR dyspepsia OR pyloric OR pylorus OR duoden* OR ulcer* OR gastritis OR reflux OR gerd OR  gastroesophageal OR esophageal OR Crohn* OR ibs

______________

If so, great job!  Fix any quotes or OR's you missed.

PubMed Search: Step #6 and #7

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The next step in a search depends on whether you use the single PubMed search box on the PubMed homepage or use the multi-box search builder on the "Advanced" search page.

Perform the following steps on the first search only (the "longterm effects of pyloric stenosis surgery" search)

  • Step #6 Enclose the terms for each concept in parentheses 

As in algebra, parentheses tell the search engine to do operations inside the parentheses first.
 
The parentheses, thus, produce a set of results for each concept.
 
  • Step #7  Join the parentheses enclosed terms lists with AND
The AND tells the search engine that any retrieved results must be part of both adjacent sets

PubMed Search: Step #6 and #7

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Does your work on the first search now look like the following:

(Surger* OR surgical* OR operat* OR post-operative OR postoperative) AND "pyloric stenosis" AND (infan* OR newborn* OR neonat* OR baby OR babies) AND (longterm OR long-term OR "long term") AND adult*

You could also enclose the single terms for the "pyloric stenosis" concept and the adult* concept in sets of parentheses, but parentheses are not necessary when a concept is represented by a single term/phrase.

PubMed Search: Step #8 -- Run Search

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  • Copy the search you created in your Word document and paste it into the PubMed search box.
  • Click the "Search" button.
Screenshot shows the PubMed search box.
 

PubMed Search: Step #8 -- Run Search

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The search should retrieve about 13 results.
 
The next step is reviewing abstracts and accessing full-text articles. 
  • click on the "Format" drop-down menu (located above the result list )
  • Select the "Abstract" view.
Screenshot showing use of the "format" menu to select the "Abstract" view.

Obtaining articles through Interlibrary Loan.

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  • Find the article entitled "Long-term investigations after pyloromyotomy for infantile pyloric stenosis."  (#4 in the result list when this tutorial was revised in 08/2018)
This is a highly relevant article, you may get as some useful information from the abstract, but it's always best to read the full-text and look for possible source of bias.
 
  • The publisher's button doesn't mention "open access" or "free" -- so click on the "GetIt@UNMC" button below the article's abstract.
A screenshot of the article abstract with an arrow poiting to the "getIt@UNMC" button.
 
 

Obtaining articles through Interlibrary Loan.

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In the new window/tab that appears, under the brief article information, you will see the "Sorry, this item is not available..." message.

The "Order item through Interlibrary Loan" button is immediately under this message.  Before you order an interlibrary loan,

  • click the "Search Google Scholar -- by Title" link
A screenshot shows the location of the "By Title" link.
A new browser tab or window will open.

Obtaining articles through Interlibrary Loan.

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In this case, none of the Google Scholar search results is relevant, but this is unusual. 
 
Usually a single search result appears that corresponds to the article of interest. 
 
Sometimes a link to a free version of the article is present  in the right-hand column (see boxed area in screenshot below).
A screenshot with a box outlining the area where links to freely available articles appear.
 

Obtaining articles through Interlibrary Loan.

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If you really wanted this article, you could order it through the library's Interlibrary Loan (ILL) Service without charge to you. 
 
90% of ILL requests are filled within 2 weekdays (M-F, 8-5)
 
You do not need this article, but, if you did, you would simply:
  • return to the "360 Link" browser tab (see screenshot below).
A screenshot showing selection of the 360 link tab.
 
  • click the "Order Item Through Interlibrary Loan" button.
 
The Interlibrary Loan login page would appear in a new tab/window.
 
  • login with your UNMC Net ID.
The first time you use the service:
  • if asked, enter your contact info to create an account (first time you used the service).
  • if a filled out request form doesn't appear:
    • click back to the "360 link" window/tab produced by the "GetIt!@UNMC" button in PubMed
    • click on the "Order item through Interlibrary Loan" button again.
    • If asked to login, you would enter your UNMC Net ID.
    • Continue as follows:
Every time you use the service:
  • The request form should be filled out for you.
  • You would just need to check the form for errors and click the "Submit" button at the bottom of the page.
  • You would receive an e-mail when the article had been posted to your account. The e-mail would contain a link to your account, so you could login and download the article
Please, download any ILL articles you order and save or print within 30 days. The article would have to be ordered again after that time.

Articles available through UNMC Licenses

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  • Return to the PubMed tab (look for the double-helix icon)
  • Scroll down to the record for an article entitled "Long-term effects of pyloromyotomy on pyloric motility and gastric emptying in humans." (#5 in the result list when this tutorial was revised in 08/2018)
A screenshot showing position of the "GetIt!@UNMC" button.

Articles available through UNMC Licenses

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A new browser tab/window will open.
 
When an article is licensed in electronic form. A right-hand side bar like the one you see now will be present.
 
Usually the article's abstract would appear on the left.
 
Sometimes as in this case, a "Click this link to open the selected resource in a new window" message will appear.
Screenshot of link that must be clicked.
  • Click the "Click this link to open the selected resource in a new window" link.

Articles available through UNMC Licenses

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A new window opens. 
 
Usually the abstract of the article and a button or link will take you to the pdf version.
 
However, sometimes, as in this case, an error message appears.
 
Screenshot of error message

Articles available through UNMC Licenses

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When you see an error message:
  • Return to the "360 link" tab.
  • Copy the article title that appears near the top of the sidebar.
  • (Notice that there is an "Order item through Interlibrary Loan" link near the bottom of the sidebar. You can always return to the "360 link" tab and use this link if the next steps don't work and you really want an article.)
  • Find the "Search the library's catalog" heading.
  • Click the subjacent "By Title" link.
Screenshot showing location of "search the Library's Catalog" "By Title" link.

 

Articles available through UNMC Licenses

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Catalog search results will appear in a new tab/window.
  • Find the entry for "The American Journal of Gastroenterology" with the "globe" icon that indicates internet access.
  • Click the "View full text" link.
Screenshot showing position of the "View Full Text" link.

Articles available through UNMC Licenses

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The journal's webpage will appear.
 
  • Find the journal's search or browse feature.
  • For this journal you will need to click on the "magnifying glass-search" icon
A screenshot of the search icon. 
 
  • Paste the article title in the search box that appears.
Screenshot of the search box and search button.
  • Hit the "Search" button.
  • Click the title of the single search result that appears.
A screenshot shows the single search result. An arrow points to the title.

Articles available through UNMC Licenses

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The article's abstract and related information will appear.
  • Find the button or link that will take you to the .pdf or full text version and click it.
A screenshot of the .pdf button for this article.
  • Sometimes a pdf will open in a new browser window. At other times, the pdf will be downloaded into your computer's "Downloads" folder and you will have to find and open it .  

Freely Available Journal Articles

Scroll down to the record for the article entitled "Chronic intestinal pseudo-obstruction: treatment and long term follow up of 44 patients"
 
This isn't a relevant article, but it provides the only example in this search of "free full text" and "PMC free full text" buttons.
 
Screenshot of a "free full text" BMJ button and a "PMC free full text" butto.
 
When you see a "free", "Open access", or "PMC free full text" button under the record for an article of interest, take advantage of it!
 

Want to check your resource knowledge?

You will continue searching PubMed in the next tutorial episode so the PubMed questions are at the end of that episode.  Here's a single question on some of the other content of this tutorial and tutorial 3.

Which of the following (a,b, or both a and b(c) ) is true concerning UpToDate?

 

Link to episode 5

Tutorial episode 5 will guide you as you use the "Advanced" search feature in PubMed to complete the search for articles about gastrointestinal problems in medical students.